Cannabinoids are chemical compounds that act on cannabinoid receptors in cells within the body.
Endocannabinoids are produced naturally inside the body whereas phytocannabinoids are found in cannabis and other plants.
Tetrahydrocannabinol (9-THC) is one of the primary active cannabinoids found in cannabis plants. THC is most commonly known for it’s psychoactive effects but studies have shown that THC reduces pain and inflammation, reduces vomiting and nausea, stimulates the appetite and suppresses muscle spasms. Lab tests on brain and breast tumours taken from animals showed THC actively killing cancer cells.
Cannabidiol (CBD) is a primary active cannabinoid identified in cannabis plants and is a powerful anti-oxidant. Studies have suggested that CBD has significant benefits when treating a range of conditions such as anxiety, inflammation, insomnia, nausea, depression and pain. It has also been reported to act as an anti-convulsant and an anti-psychotic. Unlike THC, CBD doesn’t have any psychoactive effects.
Both CBD and THC when taken combined work in synergy and have been shown to have anti-tumour properties. The potency of the THC increases when taken in combination with CBD while the CBD counteracts some of THC’s psychoactive effects.
The two main cannabinoids in cannabis plants are CBD and THC but what about the cannabinoids that occur during each bio-synthesis stage?
Cannabigerolic Acid (CBGa) is formed when geranyl pyrophosphate combines with olivetolic acid in the cannabis plant. Enzymes within the cannabis turn the CBGa into either THCa or CBDa. It relieves pain, reduces inflammation, slows bacterial growth and has been shown to inhibit the growth of cancer cells.
Cannabidiolic Acid (CBDa) is a cannabinoid that is found in raw cannabis plants. When cannabis is decarboxylated or heated a chemical reaction occurs, H2O (water) and Co2 (carbon dioxide) are released from the plant which turn it into CBD. CBDa reduces inflammation and nausea, relieves pain and acts as an anti-bacterial and antioxidant.
Tetrahydrocannabinolic Acid (9-THCa) is found in cannabis plants in its raw form before it is decarboxylated. It is thought to increase immuno-modulating effects which stimulate or suppress the immune system and helps the body to fight cancer, infections and other diseases.
Cannabigerol (CBG): By the time cannabis plants reach maturity most of the CBG has been converted into other cannabinoids during the several bio-synthesis stages, primarily THC or CBD. It has anti-inflammatory, anti septic and neuroprotective properties and can help in alleviating pain.
Cannabichromene (CBC) CBC is thought to increase the levels of natural endocannabinoids in the body. Studies have shown CBC to have anti-tumour and analgesic effects and it is also thought to relieve pain and have antidepressant effects.
Delta-8-Tetrahydrocannabinol (8-THC) just like 9-THC, Delta 8-THC binds to the CB1 cannabinoid receptor, their only differences are their bonding electrons and psycho-activity. It it is thought to have anti-nausea, anti-anxiety, appetite-stimulating, and neuroprotective properties.
Tetrahydrocannabivarin (THCv) similar to THC, THCv is a receptor type 1 antagonist. Low doses will not get you “high” but at higher doses it can switch and become an agonist which will cause a “high” effect. It acts as an appetite depressant as well as helping with anxiety, promoting the growth of new bone cells and regulating blood sugar levels.